Managing Mischief in the Oral Microbiome: with Iodine, Silver, Arginine, Xylitol, vitamin B6, and more. 

Presented by Dr. Jeremy Horst, DDS, PhD

Director, Clinical Innovation for CareQuest

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Course Description: In this course we will explore ways to bring breakthrough antimicrobial therapies into dental practice. We will unveil practical strategies to control dental caries by examining the potency of SDF and exploring why chlorhexidine doesn't work but povidone iodine does, and when prebiotics such as Xylitol, Arginine, and vitamin B6 can be effective. By reviewing the clinical trial evidence in the context of microbial mechanisms, the mystery of bacterial control in dental caries will be revealed. Practically it all comes down to substantivity and microbial nutrition.  

Objectives: At the end of this presentation, participants will be able to describe the:

  • Plan therapeutic strategies with safe, non-staining materials like Povidone Iodine. 
  • Explain to patients how the stain from SDF is connected to its potency against caries. 
  • Teach colleagues the mechanistic basis of caries antimicrobials that work. 
  • Share with patients that having an antimicrobial brushed on their teeth 1 to 4 times per year lowers new cavities by >60%. 

Jeremy Horst Keeper DDS, PhD is the director of clinical innovation at CareQuest Innovation Partners, an organization whose mission is to improve oral health for all by advancing innovation to transform oral health access and outcomes for underserved populations across the U.S. As a practicing pediatric dentist, biochemist, and educator, Jeremy is known for investigating the strengths and limitations of Silver Fluoride therapy, helping to develop SMART fillings, and accelerating the adoption of maximally effective, minimally invasive caries management techniques. In support of this work, Jeremy holds affiliations with the University of Washington department of Oral Health Sciences and the Dental Therapy program. At CareQuest, Jeremy is driving the development of better treatments, preventives, and diagnostics to improve access to person-centered care, integrate oral health into overall health, and stop dental caries.

This speaker has declared a commercial interest in or  relationship with organizations or companies that sell products or services relative to this presentation.